The in vivo Antioxidant potential of aqueous extract of Aerva lanata Linn was analyzed against ethylene glycol induced urolithiatic rats. The effect of extract on lipid peroxides and antioxidant enzymes in plasma and hepatic tissues in normal and urolithiatic rats were analyzed. Treatment with 500 mg/kg (p.o.) of aqueous extract of Aerva lanata improved the, SOD, catalase, and lipid peroxides (TBARS mtd) levels significantly as compared to control group. The present studies revealed that Aerva lanata have significant in-vivo antioxidant activity and can be used to protect tissue from oxidative stress. This study revealed that the aqueous extract of Aerva lanata comprise effective source of natural antioxidant, which might be helpful in preventing the progress of various oxidative stresses and a good source of neutraceuticals. In vivo antioxidant parameters such as lipid peroxidation (TBARS), superoxide dismutase (SOD), and catalase (CAT) were monitored. It was observed that treatment with 500 mg/kg (p.o.) of aqueous extract of Aerva lanata produced significant (P < 0.001) decrease in TBARS, and increased SOD, and CAT.
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